Current state of treatment of Dupuytren's disease.
نویسنده
چکیده
On overview is present which briefly summarizes the incidence, pathology and natural progress of Dupuytren's Disease. The importance of recognizing the Dupuytren diathesis in planning the surgical treatment, the importance of conservatism in initiating surgery, and the principles of surgical management including dermofasciectomy are presented, and it is once again stressed that a distinction exists between recurrence and extension of Dupuytren's Disease post-operatively.
منابع مشابه
Prevalence, incidence, and treatments of Dupuytren’s disease in the United States: results from a population-based study
BACKGROUND This large population-based study was conducted to estimate the prevalence of Dupuytren's disease in US adults and describe associated treatment patterns. METHODS A total of 23,103 individuals from an Internet-based research panel representative of the US population completed a brief online survey designed to identify individuals with symptoms, diagnoses, and/or treatment experienc...
متن کاملAreview of Dupuytren\'s contracture in 43 hands: assessment of the nature and result after fasciectomy
Abstract Background: Dupuytren's disease is a fibroproliferative disorder of the palmar fascia that can result in disabling contractures of the digits. When function is impeded or deformity is disabling, surgical intervention can be considered, wherein a major problem is recurrence ( reported up to 74%). Although, the disease occurs predominantly in men of northern European, there are ver...
متن کاملThe effect of splinting after Dupuytren\'s contracture surgery: A Systematic Review
Objectives: Flexion contracture in fingers of hands is a complication of Dupuytren's contracture and cannot be stopped by the progressive course. The aim of this study was to review the effect of splinting in corrective of contracture after Dupuytren's contracture surgery. Methods: To carry out this research, a kind of systematic evidence-based review process (Duffy 2005) was used. For data...
متن کاملCalcium-dependent signaling in Dupuytren's disease.
BACKGROUND Previous studies suggest that Dupuytren's disease is caused by fibroblast and myofibroblast contractility. Cell contractility in smooth muscle cells is caused by calcium-dependent and calcium-independent signaling mechanisms. In the calcium-dependent pathway, calcium/calmodulin activates myosin light chain kinase (MLCK). In this study, the effects of calcium/calmodulin inhibition wit...
متن کاملAdipose-derived stem cells inhibit the contractile myofibroblast in Dupuytren's disease.
BACKGROUND In an attempt to provide minimally invasive treatment for Dupuytren's disease, percutaneous disruption of the affected tissue followed by lipografting is being tested. Contractile myofibroblasts drive this fibroproliferative disorder, whereas stem cells have recently been implicated in preventing fibrosis. Therefore, the authors tested the role of stem cells in modulating myofibrobla...
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عنوان ژورنال:
- Annales de chirurgie de la main : organe officiel des societes de chirurgie de la main
دوره 3 1 شماره
صفحات -
تاریخ انتشار 1984